Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1

The Twist-1 transcription factor and its interacting protein Akirin-2 regulate apoptosis. We found that in glioblastomas, highly malignant brain tumors, Akirin-2 and Twist-1 were expressed in glial fibrillary acidic protein positive tumor regions as well as in tumor endothelial cells and infiltratin...

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Detalles Bibliográficos
Autores principales: Krossa, Sebastian, Schmitt, Anne Dorothée, Hattermann, Kirsten, Fritsch, Jürgen, Scheidig, Axel J., Mehdorn, Hubertus Maximilian, Held-Feindt, Janka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673248/
https://www.ncbi.nlm.nih.gov/pubmed/26036627

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