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By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer
Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial to mesenchymal transition (EMT) in androgen-independent prostate cancer (AIPC) cells in vitro and metastasis of AIPC in v...
Autores principales: | Wen, Yu-Ching, Lee, Wei-Jiunn, Tan, Peng, Yang, Shun-Fa, Hsiao, Michael, Lee, Liang-Ming, Chien, Ming-Hsien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673254/ https://www.ncbi.nlm.nih.gov/pubmed/26110567 |
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