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By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer

Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial to mesenchymal transition (EMT) in androgen-independent prostate cancer (AIPC) cells in vitro and metastasis of AIPC in v...

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Detalles Bibliográficos
Autores principales: Wen, Yu-Ching, Lee, Wei-Jiunn, Tan, Peng, Yang, Shun-Fa, Hsiao, Michael, Lee, Liang-Ming, Chien, Ming-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673254/
https://www.ncbi.nlm.nih.gov/pubmed/26110567

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