Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti-apoptotic proteins Mcl-1 and Bcl-2

Metformin and aspirin have been studied extensively as cancer preventive or therapeutic agents. However, the effects of their combination on pancreatic cancer cells have not been investigated. Herein, we evaluated the effects of metformin and aspirin, alone or in combination, on cell viability, migr...

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Detalles Bibliográficos
Autores principales: Yue, Wen, Zheng, Xi, Lin, Yong, Yang, Chung S., Xu, Qing, Carpizo, Darren, Huang, Huarong, DiPaola, Robert S., Tan, Xiang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673260/
https://www.ncbi.nlm.nih.gov/pubmed/26056043

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