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TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer
Epigenetic silencing of tumour suppressors contributes to the development and progression of lung cancer. We recently found that TMEM196 was hypermethylated in lung cancer. This study aimed to clarify its epigenetic regulation, possible roles and clinical significance. TMEM196 methylation correlated...
Autores principales: | Liu, Wen-bin, Han, Fei, Jiang, Xiao, Chen, Hong-qiang, Zhao, Huan, Liu, Yong, Li, Yong-hong, Huang, Chuanshu, Cao, Jia, Liu, Jin-yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673261/ https://www.ncbi.nlm.nih.gov/pubmed/26056045 |
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