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Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening

The limited translational value in clinic of analyses performed on 2-D cell cultures has prompted a shift toward the generation of 3-dimensional (3-D) multicellular systems. Here we present a spontaneously-forming in vitro cancer spheroid model, referred to as spheroids(MARY-X), that precisely refle...

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Detalles Bibliográficos
Autores principales: Theodoraki, Maria A., Rezende, Celso O., Chantarasriwong, Oraphin, Corben, Adriana D., Theodorakis, Emmanuel A., Alpaugh, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673263/
https://www.ncbi.nlm.nih.gov/pubmed/26101913