ZD6474, a new treatment strategy for human osteosarcoma, and its potential synergistic effect with celecoxib

ZD6474, a small molecule VEGFR and EGFR tyrosine kinase inhibitor, has been considered as a promising tumor-targeted drug in various malignancies. EGFR and cyclooxygenase-2 (COX-2) were found overexpressed in osteosarcoma in previous reports, so here we tried to explore the anti-osteosarcoma effect...

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Detalles Bibliográficos
Autores principales: Liu, Jiani, Wu, Jiangxue, Zhou, Ling, Pan, Changchuan, Zhou, Yi, Du, Wuying, Chen, Jie-min, Zhu, Xiaofeng, Shen, Jingnan, Chen, Shuai, Liu, Ran-yi, Huang, Wenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673269/
https://www.ncbi.nlm.nih.gov/pubmed/26050198

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