Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer

Cyclooxygenase-1 (COX-1) is implicated in ovarian cancer. However, patterns of COX expression and function have been unclear and controversial. In this report, patterns of COX-1 and COX-2 gene expression were obtained from RNA-seq data through The Cancer Genome Atlas. Our analysis revealed markedly...

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Detalles Bibliográficos
Autores principales: Wilson, Andrew J., Fadare, Oluwole, Beeghly-Fadiel, Alicia, Son, Deok-Soo, Liu, Qi, Zhao, Shilin, Saskowski, Jeanette, Uddin, Md. Jashim, Daniel, Cristina, Crews, Brenda, Lehmann, Brian D., Pietenpol, Jennifer A., Crispens, Marta A., Marnett, Lawrence J., Khabele, Dineo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673270/
https://www.ncbi.nlm.nih.gov/pubmed/25972361

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