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PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-κB-dependent transcription

PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) is a novel cloned gene which has been identified as a major haploinsufficient tumor suppressor essential for maintaining telomerase activity, the length of telomerase and chromosome stability. This study explored the clinical significance and biol...

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Detalles Bibliográficos
Autores principales: Li, Hai-Long, Han, Li, Chen, Hai-Rong, Meng, Fei, Liu, Qing-Hua, Pan, Zhen-Qiang, Bai, Jin, Zheng, Jun-Nian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673274/
https://www.ncbi.nlm.nih.gov/pubmed/26033551