Cargando…
PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-κB-dependent transcription
PIN2/TRF1-interacting telomerase inhibitor 1 (PinX1) is a novel cloned gene which has been identified as a major haploinsufficient tumor suppressor essential for maintaining telomerase activity, the length of telomerase and chromosome stability. This study explored the clinical significance and biol...
Autores principales: | Li, Hai-Long, Han, Li, Chen, Hai-Rong, Meng, Fei, Liu, Qing-Hua, Pan, Zhen-Qiang, Bai, Jin, Zheng, Jun-Nian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673274/ https://www.ncbi.nlm.nih.gov/pubmed/26033551 |
Ejemplares similares
-
PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway
por: Shi, Meilin, et al.
Publicado: (2015) -
PinX1: structure, regulation and its functions in cancer
por: Li, Hai-Long, et al.
Publicado: (2016) -
PinX1t, a Novel PinX1 Transcript Variant, Positively Regulates Cardiogenesis of Embryonic Stem Cells
por: Chan, Hing Chung, et al.
Publicado: (2020) -
PinX1 regulation of telomerase activity and apoptosis in nasopharyngeal carcinoma cells
por: Lai, Xiao-Fen, et al.
Publicado: (2012) -
Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity
por: Cheung, Derek Hang-Cheong, et al.
Publicado: (2017)