Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic

Liver is the major organ for arsenic methylation metabolism and may be the potential target of arsenic-induced cancer. In this study, normal human liver cell was treated with arsenic trioxide, and detected using DNA methylation microarray. Some oncogenes, tumor suppressor genes, transcription factor...

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Detalles Bibliográficos
Autores principales: Miao, Zhuang, Wu, Lin, Lu, Ming, Meng, Xianzhi, Gao, Bo, Qiao, Xin, Zhang, Weihui, Xue, Dongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673281/
https://www.ncbi.nlm.nih.gov/pubmed/26046465

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