Inhibition of Bcl-xL overcomes polyploidy resistance and leads to apoptotic cell death in acute myeloid leukemia cells

Small molecular inhibitors or drugs targeting specific molecular alterations are widely used in clinic cancer therapy. Despite the success of targeted therapy, the development of drug resistance remains a challenging problem. Identifying drug resistance mechanisms for targeted therapy is an area of...

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Detalles Bibliográficos
Autores principales: Zhou, Weihua, Xu, Jie, Gelston, Elise, Wu, Xing, Zou, Zhengzhi, Wang, Bin, Zeng, Yunxin, Wang, Hua, Liu, Anwen, Xu, Lingzhi, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673286/
https://www.ncbi.nlm.nih.gov/pubmed/26188358

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