Identification of alsterpaullone as a novel small molecule inhibitor to target group 3 medulloblastoma

Advances in the molecular biology of medulloblastoma revealed four genetically and clinically distinct subgroups. Group 3 medulloblastomas are characterized by frequent amplifications of the oncogene MYC, a high incidence of metastasis, and poor prognosis despite aggressive therapy. We investigated...

Descripción completa

Detalles Bibliográficos
Autores principales: Faria, Claudia C., Agnihotri, Sameer, Mack, Stephen C., Golbourn, Brian J., Diaz, Roberto J., Olsen, Samantha, Bryant, Melissa, Bebenek, Matthew, Wang, Xin, Bertrand, Kelsey C., Kushida, Michelle, Head, Renee, Clark, Ian, Dirks, Peter, Smith, Christian A., Taylor, Michael D., Rutka, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673298/
https://www.ncbi.nlm.nih.gov/pubmed/26061748

Ejemplares similares

Ejemplares similares