Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells

Recent epidemiological studies indicate that the antidiabetic drug metformin has chemosensitizing and chemopreventive effects against carcinogenesis. Here, we demonstrate that metformin exerts varying degrees of antitumor activity against human leukemia cells, as reflected by differences in growth i...

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Detalles Bibliográficos
Autores principales: Rodríguez-Lirio, A., Pérez-Yarza, G., Fernández-Suárez, M. R., Alonso-Tejerina, E., Boyano, M. D., Asumendi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673355/
https://www.ncbi.nlm.nih.gov/pubmed/26688757
http://dx.doi.org/10.1155/2015/516460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673355/
https://www.ncbi.nlm.nih.gov/pubmed/26688757
http://dx.doi.org/10.1155/2015/516460

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