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Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells
Recent epidemiological studies indicate that the antidiabetic drug metformin has chemosensitizing and chemopreventive effects against carcinogenesis. Here, we demonstrate that metformin exerts varying degrees of antitumor activity against human leukemia cells, as reflected by differences in growth i...
Autores principales: | Rodríguez-Lirio, A., Pérez-Yarza, G., Fernández-Suárez, M. R., Alonso-Tejerina, E., Boyano, M. D., Asumendi, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673355/ https://www.ncbi.nlm.nih.gov/pubmed/26688757 http://dx.doi.org/10.1155/2015/516460 |
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