Cargando…

Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses

The majority of new HIV-1 infections are transmitted sexually by penetrating the mucosal barrier to infect target cells. The development of microbicides to restrain heterosexual HIV-1 transmission in the past two decades has proven to be a challenging endeavor. Therefore, better understanding of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eid, Sahar G, Mangan, Niamh E, Hertzog, Paul J, Mak, Johnson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673443/ https://www.ncbi.nlm.nih.gov/pubmed/26682051 http://dx.doi.org/10.1038/cti.2015.23

Ejemplares similares

Spatiotemporal regulation of human IFN-ε and innate immunity in the female reproductive tract
por: Bourke, Nollaig M., et al.
Publicado: (2022)

New Candidate Biomarkers in the Female Genital Tract to Evaluate Microbicide Toxicity
por: Fields, Scott, et al.
Publicado: (2014)

Which Topical Microbicides for Blocking HIV-1 Transmission Will Work in the Real World?
por: Klasse, Per Johan, et al.
Publicado: (2006)

Structure Activity Relationship of Dendrimer Microbicides with Dual Action Antiviral Activity
por: Tyssen, David, et al.
Publicado: (2010)

The Development of Vaginal Microbicides for the Prevention of HIV Transmission
por: Weber, Jonathan, et al.
Publicado: (2005)

Can a Topical Microbicide Prevent Rectal HIV Transmission?
por: Hladik, Florian, et al.
Publicado: (2008)

Topical microbicides to prevent the transmission of HIV: formulation gaps and challenges
por: Turpin, Jim A.
Publicado: (2011)

Adipokines and the Female Reproductive Tract
por: Reverchon, Maxime, et al.
Publicado: (2014)

Organoids of the female reproductive tract
por: Chumduri, Cindrilla, et al.
Publicado: (2021)

Antiviral Compounds for Blocking Arboviral Transmission in Mosquitoes
por: Dong, Shengzhang, et al.
Publicado: (2021)

Entry inhibitors as topical microbicides to prevent HIV-1 sexual transmission
por: Moore, John P
Publicado: (2006)

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission
por: Cone, Richard A, et al.
Publicado: (2006)

Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
por: Rahman, Mohammad Arif, et al.
Publicado: (2023)

Leptotrichia amnionii and the Female Reproductive Tract
por: Gundi, Vijay A.K.B., et al.
Publicado: (2004)

Immune Cells in the Female Reproductive Tract
por: Lee, Sung Ki, et al.
Publicado: (2015)

The metagenome of the female upper reproductive tract
por: Li, Fei, et al.
Publicado: (2018)

Female reproductive tract-organ axes
por: Takada, Kazuhide, et al.
Publicado: (2023)

Anatomy of the Female Koala Reproductive Tract
por: Pagliarani, Sara, et al.
Publicado: (2023)

P13-06. DARPin-based microbicide strategies to block HIV entry
por: Mann, A, et al.
Publicado: (2009)

The Formulated Microbicide RC-101 Was Safe and Antivirally Active Following Intravaginal Application in Pigtailed Macaques
por: Cole, Alexander M., et al.
Publicado: (2010)

Proteases commit microbicide
por: LeBrasseur, Nicole
Publicado: (2002)

Microbicides 2006 conference
por: Ramjee, Gita, et al.
Publicado: (2006)

Microbicides for HIV prevention
por: Ramjee, Gita
Publicado: (2011)

Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse
por: Moench, Thomas R, et al.
Publicado: (2010)

Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli
por: O'Hanlon, Deirdre E, et al.
Publicado: (2010)

Sexually Transmitted Infections and Reproductive Health Morbidity in a Cohort of Female Sex Workers Screened for a Microbicide Feasibility Study in Nellore, India
por: Sarna, Avina, et al.
Publicado: (2013)

Comparative female reproductive tract development and morphology
por: Hoar, Richard M.
Publicado: (1978)

Role of the innate immunity in female reproductive tract
por: Amjadi, Fatemehsadat, et al.
Publicado: (2014)

Sperm Storage in the Female Reproductive Tract in Birds
por: SASANAMI, Tomohiro, et al.
Publicado: (2013)

Adaptation of Neisseria gonorrhoeae to the Female Reproductive Tract
por: Song, Wenxia, et al.
Publicado: (2020)

Understanding the Female Reproductive Tract’s Role in Fertilization
por: Dalton, Louisa
Publicado: (2022)

Female reproductive tract microbiome and early miscarriages
por: Lebedeva, Olga P., et al.
Publicado: (2023)

The Female Reproductive Tract Microbiota: Friends and Foe
por: Kumar, Lokesh, et al.
Publicado: (2023)

Feasibility of Repurposing the Polyanionic Microbicide, PPCM, for Prophylaxis against HIV Transmission during ART
por: Anderson, Robert A., et al.
Publicado: (2011)

Publisher Correction: Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
por: Rahman, Mohammad Arif, et al.
Publicado: (2023)

Live microbial microbicides for HIV
por: Hamer, Dean, et al.
Publicado: (2006)

Microbicides & their implications in HIV prevention
por: Karim, Salim S. Abdool, et al.
Publicado: (2010)

New Interferons
por: Hertzog, Paul J., et al.
Publicado: (2016)

Postcoital Bioavailability and Antiviral Activity of 0.5% PRO 2000 Gel: Implications for Future Microbicide Clinical Trials
por: Keller, Marla J., et al.
Publicado: (2010)

Safety Assessment of Microbicide 2P23 on the Rectal and Vaginal Microbiota and Its Antiviral Activity on HIV Infection
por: Gao, Zhengqin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mfq0epktl0iqeufkltqgpmm51j