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Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?
Human rhinovirus (HRV) infection is a major cause of asthma exacerbations, which appears to be linked to a defective innate immune response to infection. Although the type I interferons (IFN-α and IFN-β) have a critical role in protecting against most viral infections, the cells responsible for IFN...
Autores principales: | Xi, Yang, Finlayson, Arvid, White, Oliva J, Carroll, Melanie L, Upham, John W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673444/ https://www.ncbi.nlm.nih.gov/pubmed/26682054 http://dx.doi.org/10.1038/cti.2015.27 |
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