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REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia

The hypoxia-inducible factor (HIF) is a key regulator of the cellular response to hypoxia which promotes oxygen delivery and metabolic adaptation to oxygen deprivation. However, the degree and duration of HIF-1α expression in hypoxia must be carefully balanced within cells in order to avoid unwanted...

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Detalles Bibliográficos
Autores principales:	Cavadas, Miguel A. S., Mesnieres, Marion, Crifo, Bianca, Manresa, Mario C., Selfridge, Andrew C., Scholz, Carsten C., Cummins, Eoin P., Cheong, Alex, Taylor, Cormac T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673454/ https://www.ncbi.nlm.nih.gov/pubmed/26647819 http://dx.doi.org/10.1038/srep17851

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