Cargando…
Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation
Caveolae are flask-shaped cell-surface membranes, which consist of cholesterol, sphingolipids and caveolin proteins. In a microarray analysis, we found that caveolin-1 (Cav-1) was upregulated by receptor activator of NFκB ligand (RANKL), the osteoclast differentiation factor. Silencing of Cav-1 inhi...
Autores principales: | Lee, Yong Deok, Yoon, Soo-Hyun, Ji, Eunhee, Kim, Hong-Hee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673477/ https://www.ncbi.nlm.nih.gov/pubmed/26514084 http://dx.doi.org/10.1038/emm.2015.77 |
Ejemplares similares
-
Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis
por: Gerngross, Lindsey, et al.
Publicado: (2015) -
Blocking of the Ubiquitin-Proteasome System Prevents Inflammation-Induced Bone Loss by Accelerating M-CSF Receptor c-Fms Degradation in Osteoclast Differentiation
por: Lee, Kyunghee, et al.
Publicado: (2017) -
c-Fms Signaling Mediates Neurofibromatosis Type-1 Osteoclast Gain-In-Functions
por: He, Yongzheng, et al.
Publicado: (2012) -
Canadian Federation of Medical Students (CFMS) response to: The unmatched by Dr. Amit Persad
por: Purdy, Kaylynn, et al.
Publicado: (2018) -
Deficiency of Lipocalin-2 Promotes Proliferation and Differentiation of Osteoclast Precursors via Regulation of c-Fms Expression and Nuclear Factor-kappa B Activation
por: Kim, Hyun-Ju, et al.
Publicado: (2016)