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The lymphocyte secretome from young adults enhances skeletal muscle proliferation and migration, but effects are attenuated in the secretome of older adults
Older people experience skeletal muscle wasting, in part due to impaired proliferative capacity of quiescent skeletal muscle satellite cells which can be reversed by exposure to young blood. To investigate the role of immune cells in muscle regeneration, we isolated lymphocytes from whole blood of y...
Autores principales: | Al-Dabbagh, Sarah, McPhee, Jamie S, Murgatroyd, Christopher, Butler-Browne, Gillian, Stewart, Claire E, Al-Shanti, Nasser |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673618/ https://www.ncbi.nlm.nih.gov/pubmed/26603449 http://dx.doi.org/10.14814/phy2.12518 |
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