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Role of the Na(+)/H(+) exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines

The role of Na(+/)H(+) exchanger 3 (NHE3) in the kidney in angiotensin II (ANG II)-induced hypertension remains unknown. The present study used global NHE3-deficient mice with transgenic rescue of the Nhe3 gene in small intestines (tgNhe3(−/−)) to test the hypothesis that genetic deletion of NHE3 se...

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Detalles Bibliográficos
Autores principales: Li, Xiao C, Shull, Gary E, Miguel-Qin, Elisa, Chen, Fang, Zhuo, Jia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673635/
https://www.ncbi.nlm.nih.gov/pubmed/26564064
http://dx.doi.org/10.14814/phy2.12605