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Control of developmentally primed erythroid genes by combinatorial co-repressor actions

How transcription factors (TFs) cooperate within large protein complexes to allow rapid modulation of gene expression during development is still largely unknown. Here we show that the key haematopoietic LIM-domain-binding protein-1 (LDB1) TF complex contains several activator and repressor componen...

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Detalles Bibliográficos
Autores principales: Stadhouders, Ralph, Cico, Alba, Stephen, Tharshana, Thongjuea, Supat, Kolovos, Petros, Baymaz, H. Irem, Yu, Xiao, Demmers, Jeroen, Bezstarosti, Karel, Maas, Alex, Barroca, Vilma, Kockx, Christel, Ozgur, Zeliha, van Ijcken, Wilfred, Arcangeli, Marie-Laure, Andrieu-Soler, Charlotte, Lenhard, Boris, Grosveld, Frank, Soler, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673834/
https://www.ncbi.nlm.nih.gov/pubmed/26593974
http://dx.doi.org/10.1038/ncomms9893