Cargando…

Design, Synthesis and Evaluation of Antitubercular Activity of Novel Dihydropyridine Containing Imidazolyl Substituent

Recent studies have indicated that 1, 4-dihydropyridine-3, 5-dicarboxamide derivatives show significant anti-tubercular activity. In this research, new derivatives of 1, 4-dihydropyridine were designed and synthesized using Hantzsch condensation in which dicyclohexyl and different dicyclohexylcarbam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iman, Maryam, Davood, Asghar, Dehqani, Golnoush, Lotfinia, Mahboubeh, Sardari, Soroush, Azerang, Parisa, Amini, Mohsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673934/ https://www.ncbi.nlm.nih.gov/pubmed/26664373

Ejemplares similares

Design, Synthesis and Anti-Tubercular Activity of Novel 1, 4-Dihydropyrine-3, 5-Dicarboxamide Containing 4(5)-Chloro-2-Ethyl- 5(4)-Imidazolyl Moiety
por: Iman, Maryam, et al.
Publicado: (2016)

Anticonvulsant Effects of New 1, 4-DihydropyridineDerivatives Containing Imidazolyl Moiety Against Seizures Induced by Pentylenetetrazole and Maximal Electroshock in Mice
por: Rasouli, Yasaman, et al.
Publicado: (2017)

Synthesis of Novel 4-[1-(4-fluorobenzyl)-5-imidazolyl] Dihydropyridines and Studying their Effects on Rat Blood Pressure
por: Mohajeri, Seyed Ahmad, et al.
Publicado: (2011)

Quantitative Structure-Activity Relationship Studies of 4-Imidazolyl- 1,4-dihydropyridines as Calcium Channel Blockers
por: Hadizadeh, Farzin, et al.
Publicado: (2013)

Antifungal Indole and Pyrrolidine-2,4-Dione Derivative Peptidomimetic Lead Design Based on In Silico Study of Bioactive Peptide Families
por: Moradi, Shoeib, et al.
Publicado: (2013)

Evaluation of anticonvulsant effect of two novels 4-[1-(4-fluorobenzyl)- 5-imidazolyl] dihydropyridine derivatives in mice
por: Hadizadeh, F, et al.
Publicado: (2013)

Synthesis and biological evaluation of propargyl acetate derivatives as anti-mycobacterial agents
por: Azerang, Parisa, et al.
Publicado: (2012)

Synthesis of Novel Fluorene Bisamide Derivatives via Ugi Reaction and Evaluation their Biological Activity against Mycobacterium species
por: Rezayan, Ali Hossein, et al.
Publicado: (2017)

Synthesis and Antimycobacterial Activity of Symmetric Thiocarbohydrazone Derivatives against Mycobacterium bovis BCG
por: Haj Mohammad Ebrahim Tehrani, Kamaleddin, et al.
Publicado: (2013)

Synthesis and Antimicrobial Evaluation of 4H-Pyrans and Schiff Bases Fused 4H-Pyran Derivatives as Inhibitors of Mycobacterium bovis (BCG)
por: Mahdavi, Seyedeh Mahbobeh, et al.
Publicado: (2018)

Synthesis and Antimycobacterial Activity of some Triazole Derivatives–New Route to Functionalized Triazolopyridazines
por: Tehrani, Kamaleddin Haj Mohammad Ebrahim, et al.
Publicado: (2015)

Molecular Characterization of a Fungus Producing Membrane Active Metabolite and Analysis of the Produced Secondary Metabolite
por: Azerang, Parisa, et al.
Publicado: (2019)

Synthesis and Biological Evaluation of Thiosemicarbazide Derivatives Endowed with High Activity toward Mycobacterium Bovis
por: Sardari, Soroush, et al.
Publicado: (2017)

Copper(II) Complexes of Amino Acids and Peptides Containing Chelating bis(imidazolyl) Residues
por: Sóvágó, lmre, et al.
Publicado: (2003)

Identification and Evaluation of Novel Drug Targets against the Human Fungal Pathogen Aspergillus fumigatus with Elaboration on the Possible Role of RNA-Binding Protein
por: Malekzadeh, Saeid, et al.
Publicado: (2017)

7-Imidazolyl-substituted 4'-methoxy and 3',4'-dimethoxy-containing polyfluoroflavones as promising antiviral agents
por: Shcherbakov, Konstantin V., et al.
Publicado: (2020)

Synthesis and Biological Evaluation of Novel Alkyl-Imidazolyl Carbinols and their Esters: Potent Antimycotics
por: Krauss, Jürgen, et al.
Publicado: (2013)

Imidazolyl‐Substituted Benzo‐ and Naphthodithiophenes as Precursors for the Synthesis of Transient Open‐Shell Quinoids
por: Hou, Peng, et al.
Publicado: (2023)

Synthesis of tetrasubstituted pyrazoles containing pyridinyl substituents
por: Jansa, Josef, et al.
Publicado: (2017)

1,2‐Addition of Diethylzinc to a Bis(Imidazolyl)ketone Ligand
por: Folkertsma, Emma, et al.
Publicado: (2018)

Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity
por: dos Santos Fernandes, Guilherme Felipe, et al.
Publicado: (2017)

Lipid Membrane Adsorption Determines Photodynamic Efficiency of β-Imidazolyl-Substituted Porphyrins
por: Jiménez-Munguía, Irene, et al.
Publicado: (2019)

Imidazolyl activated carbon refluxed with ethanediamine as reusable heterogeneous catalysts for Michael addition
por: Liu, Wenzhu, et al.
Publicado: (2018)

Synthesis of asymmetric [bis(imidazolyl)-BH(2)](+)-cation-based ionic liquids as potential rocket fuels
por: Li, Xue, et al.
Publicado: (2021)

Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors
por: Hamdy, Jehad, et al.
Publicado: (2022)

Synthesis and Characterization of Novel Triphenylamine—Containing Electrochromic Polyimides with Benzimidazole Substituents
por: Yan, Kuangguo, et al.
Publicado: (2023)

Different molecular conformations in the crystal structures of three 5-nitroimidazolyl derivatives
por: Osorio, Luis F. B., et al.
Publicado: (2018)

Design of Small Molecules with HIV Fusion Inhibitory Property Based on Gp41 Interaction Assay
por: Sardari, Soroush, et al.
Publicado: (2013)

Plumbagin analogs-synthesis, characterization, and antitubercular activity
por: Nayak, Nishi, et al.
Publicado: (2014)

Synthesis and Structural Analysis of (Imido)vanadium Dichloride Complexes Containing 2-(2′-Benz-imidazolyl)pyridine Ligands: Effect of Al Cocatalyst for Efficient Ethylene (Co)polymerization
por: Nomura, Kotohiro, et al.
Publicado: (2017)

Substituted Dihydropyridine Synthesis by Dearomatization of Pyridines
por: Heusler, Arne, et al.
Publicado: (2021)

ω‐Imidazolyl‐alkyl derivatives as new preclinical drug candidates for treating non‐alcoholic steatohepatitis
por: Diesinger, Torsten, et al.
Publicado: (2021)

Site-specific functionalization with amino, guanidinium, and imidazolyl groups enabling the activation of 10–23 DNAzyme
por: Du, Shanshan, et al.
Publicado: (2020)

Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones
por: Polaquini, Carlos R., et al.
Publicado: (2017)

Pharmacovigilance of Antitubercular Therapy in Tuberculosis
por: Ravichandran, Mirunalini, et al.
Publicado: (2022)

Antituberculars: Hepatitis: case report
Publicado: (2022)

Synthesis and Structural Activity Relationship Study of Antitubercular Carboxamides
por: Ugwu, D. I., et al.
Publicado: (2014)

Excited state dynamics for visible-light sensitization of a photochromic benzil-subsituted phenoxyl-imidazolyl radical
por: Kobayashi, Yoichi, et al.
Publicado: (2019)

Synthesis, analgesic and anti-inflammatory activities of new methyl-imidazolyl-1,3,4-oxadiazoles and 1,2,4-triazoles
por: Almasirad, Ali, et al.
Publicado: (2014)

Cytotoxic Effect of Some 1, 4-Dihydropyridine Derivatives Containing Nitroimidazole Moiety
por: Miri, Ramin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8s65f7mrdjdchktqmc05i7884f