Cargando…

Synthesis, Antiplatelet Activity and Cytotoxicity Assessment of Indole-Based Hydrazone Derivatives

A series of indole-based aryl(aroyl)hydrazone analogs of antiplatelet indole-3-carboxaldehyde phenylhydrazone were synthesized by the Schiff base formation reaction and their antiplatelet activity was assessed using human platelet rich plasma. The platelet concentrate was obtained using a two-step c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haj Mohammad Ebrahim Tehrani, Kamaleddin, Esfahani Zadeh, Marjan, Mashayekhi, Vida, Hashemi, Maryam, Kobarfard, Farzad, Gharebaghi, Farhad, Mohebbi, Shohreh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673935/ https://www.ncbi.nlm.nih.gov/pubmed/26664374

Ejemplares similares

Novel N-substituted indole hydrazones as potential antiplatelet agents: synthesis, biological evaluations, and molecular docking studies
por: Tavili, Navid, et al.
Publicado: (2021)

Synthesis and Antimycobacterial Activity of some Triazole Derivatives–New Route to Functionalized Triazolopyridazines
por: Tehrani, Kamaleddin Haj Mohammad Ebrahim, et al.
Publicado: (2015)

Synthesis and Antibacterial Activity of Novel Hydroxy Semicarbazone Derivatives
por: Hariri, Elham, et al.
Publicado: (2016)

Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents
por: Faghih Akhlaghi, Masoud, et al.
Publicado: (2014)

Synthesis and Antiplatelet Aggregation Activity Evaluation of some 2-Aminopyrimidine and 2-Substituted-4,6-diaminopyrimidine Derivatives
por: Esfahanizadeh, Marjan, et al.
Publicado: (2015)

N-Substituted indole carbohydrazide derivatives: synthesis and evaluation of their antiplatelet aggregation activity
por: Mirfazli, Seyedeh Sara, et al.
Publicado: (2014)

Synthesis and Antimycobacterial Activity of Symmetric Thiocarbohydrazone Derivatives against Mycobacterium bovis BCG
por: Haj Mohammad Ebrahim Tehrani, Kamaleddin, et al.
Publicado: (2013)

Design, Synthesis and Cytotoxicity Evaluationof New 1,2-diaryl-4, 5, 6, 7-Tetrahydro-1H-benzo[d] Imidazolesas Tubulin Inhibitors
por: Amirmostofian, Marzieh, et al.
Publicado: (2015)

Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry
por: Asgari, Arezoo, et al.
Publicado: (2015)

Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem
por: Tehrani, Kamaleddin Haj Mohammad Ebrahim, et al.
Publicado: (2017)

Synthesis, X-ray Structure, Hirshfeld, DFT Conformational, Cytotoxic, and Anti-Toxoplasma Studies of New Indole-Hydrazone Derivatives
por: Hassan, Eman M., et al.
Publicado: (2023)

Partial Fractionation of Venoms from Two Iranian Vipers, Echis carinatus and Cerastes persicus Fieldi and Evaluation of Their Antiplatelet Activity
por: Mehdizadeh Kashani, Toktam, et al.
Publicado: (2012)

Synthesis and Antiplatelet Activity Evaluation of a Group of Novel Ethyl Acetoacetate Phenylhydrazone Derivatives
por: Farhady, Sarveen, et al.
Publicado: (2021)

New Indole-3-Propionic Acid and 5-Methoxy-Indole Carboxylic Acid Derived Hydrazone Hybrids as Multifunctional Neuroprotectors
por: Anastassova, Neda, et al.
Publicado: (2023)

Electrochemical Synthesis of Novel 1,3-Indandione Derivatives and Evaluation of Their Antiplatelet Aggregation Activities
por: Amidi, Salimeh, et al.
Publicado: (2013)

Synthesis and antioxidant activity evaluations of melatonin based analogue indole-hydrazide/hydrazone derivatives
por: Yılmaz, AD, et al.
Publicado: (2012)

Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition
por: Wade, Nicola, et al.
Publicado: (2021)

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit
por: Chelucci, Rafael Consolin, et al.
Publicado: (2014)

Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem
por: Tehrani, Kamaleddin H. M. E., et al.
Publicado: (2020)

Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance
por: van Haren, Matthijs J., et al.
Publicado: (2021)

Synthesis and Cytotoxic Evaluation of Novel 3-Substituted Derivatives of 2-Indolinone
por: Mokhtari, Shaya, et al.
Publicado: (2012)

Design, Synthesis, and Density Functional Theory Studies of Indole Hydrazones as Colorimetric “Naked Eye” Sensors for F Ions
por: Alharthy, Rima D., et al.
Publicado: (2023)

FTIR Biospectroscopy Investigation on Cisplatin Cytotoxicity in Three Pairs of Sensitive and Resistant Cell Line
por: Farhadi, Ensieh, et al.
Publicado: (2016)

Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus
por: Dyniewicz, Jolanta, et al.
Publicado: (2020)

Synthesis, characterization, molecular docking evaluation, antiplatelet and anticoagulant actions of 1,2,4 triazole hydrazone and sulphonamide novel derivatives
por: Khalid, Waseem, et al.
Publicado: (2018)

Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae
por: Demir-Yazıcı, Kübra, et al.
Publicado: (2020)

In-Vitro Assessment of Magnetic Dextran-Spermine Nanoparticles for Capecitabine Delivery to Cancerous Cells
por: Ghadiri, Maryam, et al.
Publicado: (2017)

Synthesis and Cytotoxic Activity of New Thiazolopyrimidine Sugar Hydrazones and Their Derived Acyclic Nucleoside Analogues
por: Basiony, Ebtesam A., et al.
Publicado: (2020)

Synthesis and Characterization of Novel Hydrazone Derivatives of Isonicotinic Hydrazide and Their Evaluation for Antibacterial and Cytotoxic Potential
por: Shah, Muhammad Abdullah, et al.
Publicado: (2022)

Design, Synthesis and Cytotoxic Activity of Novel Salicylaldehyde Hydrazones against Leukemia and Breast Cancer
por: Nikolova-Mladenova, Boryana, et al.
Publicado: (2023)

[Ag(L)NO(3)] Complexes with 2-Benzoylpyridine-Derived Hydrazones: Cytotoxic Activity and Interaction with Biomolecules
por: Santos, Ane F., et al.
Publicado: (2018)

ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells
por: Despaigne, Angel A. Recio, et al.
Publicado: (2014)

1-(2-Hydroxy-5-methylphenyl)ethanone [(1H-indol-3-yl)acetyl]hydrazone
por: Ali, Hapipah M., et al.
Publicado: (2008)

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII
por: Demir-Yazıcı, Kübra, et al.
Publicado: (2019)

Cytotoxic and Antioxidant Activity of a Set of Hetero Bicylic Methylthiadiazole Hydrazones: A Structure-Activity Study
por: Kodisundaram, Paulrasu, et al.
Publicado: (2015)

Correction to [Ag(L)NO(3)] Complexes with 2-Benzoylpyridine-Derived Hydrazones: Cytotoxic Activity and Interaction with Biomolecules
por: Santos, Ane F., et al.
Publicado: (2018)

Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl Hydrazones
por: Argirova, Maria, et al.
Publicado: (2022)

Cytotoxic and antibacterial polyketide-indole hybrids synthesized from indole-3-carbinol by Daldinia eschscholzii
por: Lin, Liping, et al.
Publicado: (2019)

Novel Carbapenemases FLC-1 and IMI-2 Encoded by an Enterobacter cloacae Complex Isolated from Food Products
por: Brouwer, Michael S. M., et al.
Publicado: (2019)

Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases
por: Tehrani, Kamaleddin H. M. E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jccr7ra0s2sfmj1dh7m6pnsk1d