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Novel N-2-(Furyl)-2-(chlorobenzyloxyimino) Ethyl Piperazinyl Quinolones: Synthesis, Cytotoxic Evaluation and Structure-Activity Relationship

Quinolone antibacterials are one of the most important classes of pharmacological agents known as potent inhibitors of bacterial DNA gyrase and topoisomerase IV that efficiently inhibit DNA replication and transcription by generating several double-stranded DNA break. Some quinolone derivatives demo...

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Detalles Bibliográficos
Autores principales:	Mohammadhosseini, Negar, Pordeli, Mahboobeh, Safavi, Maliheh, Firoozpour, Loghman, Amin, Fatame, Kabudanian Ardestani, Sussan, Edraki, Najmeh, Shafiee, Abbas, Foroumadi, Alireza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673937/ https://www.ncbi.nlm.nih.gov/pubmed/26664376

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