Cargando…

Antinociceptive Effect of Vardenafil on Carrageenan-Induced Hyperalgesia in Rat: involvement of Nitric Oxide/Cyclic Guanosine Monophosphate/Calcium Channels Pathway

In this study, we aimed to investigate the peripheral antinociception effects of specific phosphodiesterase 5 (PDE-5) inhibitor vardenafil on carrageenan-induced nociception in rats, and the role of calcium besides the L-arginine- nitric oxide (NO)- cyclic guanosine monophophate (cGMP) pathway in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gediz, Ezgi İkiz, Nacitarhan, Cahit, Minareci, Edibe, Sadan, Gulay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673941/ https://www.ncbi.nlm.nih.gov/pubmed/26664380

Ejemplares similares

An evaluation of vardenafil as a calcium channel blocker in pulmonary artery in rats
por: Minareci, Edibe, et al.
Publicado: (2014)

Acute Effects of Vardenafil on Pulmonary Artery Responsiveness in Pulmonary Hypertension
por: Karasu-Minareci, Edibe, et al.
Publicado: (2012)

Peripheral Antinociception of a Chalcone, Flavokawin B and Possible Involvement of the Nitric Oxide/Cyclic Guanosine Monophosphate/Potassium Channels Pathway
por: Kamaldin, Mohd Nasier, et al.
Publicado: (2013)

Effect of progesterone on nitric oxide/cyclic guanosine monophosphate signaling and contraction in gastric smooth muscle cells
por: Al-Shboul, Othman A, et al.
Publicado: (2020)

Monovalent selectivity of the cyclic guanosine monophosphate-activated ion channel
Publicado: (1990)

Regulation of Biofilm Exopolysaccharide Production by Cyclic Di-Guanosine Monophosphate
por: Poulin, Myles B., et al.
Publicado: (2021)

The endothelial nitric oxide synthase/cyclic guanosine monophosphate/protein kinase G pathway activates primordial follicles
por: Zhao, Peikun, et al.
Publicado: (2020)

Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes
por: Zhang, Yujing, et al.
Publicado: (2022)

Penile Erection Induced by Scoparone from Artemisia capillaris through the Nitric Oxide-Cyclic Guanosine Monophosphate Signaling Pathway
por: Choi, Bo Ram, et al.
Publicado: (2017)

The nitric oxide‐cyclic guanosine monophosphate pathway inhibits the bladder ATP release in response to a physiological or pathological stimulus
por: Okuyama, Eriko, et al.
Publicado: (2021)

The Cardiorenal Effects of Piper amalago Are Mediated by the Nitric Oxide/Cyclic Guanosine Monophosphate Pathway and the Voltage-Dependent Potassium Channels
por: Monteiro, Luciane M., et al.
Publicado: (2023)

Possible Participation of Ionotropic Glutamate Receptors and l-Arginine-Nitric Oxide-Cyclic Guanosine Monophosphate-ATP-Sensitive K(+) Channel Pathway in the Antinociceptive Activity of Cardamonin in Acute Pain Animal Models
por: Pui Ping, Chung, et al.
Publicado: (2020)

Guanosine 3',5'-cyclic monophosphate and the in vitro physiology of frog photoreceptor membranes
Publicado: (1977)

Associations Between the Cyclic Guanosine Monophosphate Pathway and Cardiovascular Risk Factors: MESA
por: Ying, Wendy, et al.
Publicado: (2019)

Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing
por: Verrier, Eloi R., et al.
Publicado: (2021)

Rubus occidentalis and Ellagic Acid Affect the Contractility of Penile Corpus Cavernosum Smooth Muscle through the Nitric Oxide-Cyclic Guanosine Monophosphate and Cyclic Adenosine 3′,5′-Monophosphate Signaling Pathway
por: Karna, Keshab Kumar, et al.
Publicado: (2022)

Nitric Oxide and Cyclic Guanosine Monophosphate Signaling Mediates the Antidepressant Effects of Acupuncture in the Rat Model of Chronic Unpredictable Mild Stress
por: Huang, Wenya, et al.
Publicado: (2019)

Treatment of Cardiovascular Dysfunction with PDE3-Inhibitors in Moderate and Severe Hypothermia—Effects on Cellular Elimination of Cyclic Adenosine Monophosphate and Cyclic Guanosine Monophosphate
por: Kuzmiszyn, Adrina Kalasho, et al.
Publicado: (2022)

In Search of Enzymes with a Role in 3′, 5′-Cyclic Guanosine Monophosphate Metabolism in Plants
por: Gross, Inonge, et al.
Publicado: (2016)

Elevated intracranial dopamine impairs the glutamate-nitric oxide-cyclic guanosine monophosphate pathway in cortical astrocytes in rats with minimal hepatic encephalopathy
por: DING, SAIDAN, et al.
Publicado: (2014)

Identification of downstream target genes regulated by the nitric oxide–soluble guanylate cyclase–cyclic guanosine monophosphate signal pathway in pulmonary hypertension
por: Zou, Lihui, et al.
Publicado: (2016)

NMDA receptors and L-arginine/nitric oxide/cyclic guanosine monophosphate pathway contribute to the antidepressant-like effect of Yueju pill in mice
por: Wang, Wei, et al.
Publicado: (2019)

Cyclic Guanosine Monophosphate Modulates Locomotor Acceleration Induced by Nitric Oxide but not Serotonin in Clione limacina Central Pattern Generator Swim Interneurons
por: Pirtle, Thomas J, et al.
Publicado: (2021)

Nebivolol combined with tetrahydrobiopterin affects diastolic function in spontaneously hypertensive rats via the nitric oxide/cyclic guanosine monophosphate signalling pathway
por: Guan, Xiaoli, et al.
Publicado: (2020)

Increased Adhesion and Aggregation of Platelets Lacking Cyclic Guanosine 3′,5′-Monophosphate Kinase I
por: Massberg, Steffen, et al.
Publicado: (1999)

Influence of calcium on guanosine 3',5'-cyclic monophosphate levels in frog rod outer segments
Publicado: (1981)

Cell Surface Protein Disulfide Isomerase Regulates Natriuretic Peptide Generation of Cyclic Guanosine Monophosphate
por: Pan, Shuchong, et al.
Publicado: (2014)

Involvement of Cyclic Guanosine Monophosphate-Dependent Protein Kinase I in Renal Antifibrotic Effects of Serelaxin
por: Wetzl, Veronika, et al.
Publicado: (2016)

Inhibition of hypoxia-inducible factor 1α accumulation by glyceryl trinitrate and cyclic guanosine monophosphate
por: Kim, Judy, et al.
Publicado: (2020)

Cyclic Guanosine Monophosphate and Risk of Incident Heart Failure and Other Cardiovascular Events: the ARIC Study
por: Zhao, Di, et al.
Publicado: (2020)

Regulation of the physiology and virulence of Ralstonia solanacearum by the second messenger 2′,3′-cyclic guanosine monophosphate
por: Li, Xia, et al.
Publicado: (2023)

Analysis of the nitric oxide-cyclic guanosine monophosphate pathway in experimental liver cirrhosis suggests phosphodiesterase-5 as potential target to treat portal hypertension
por: Schaffner, Denise, et al.
Publicado: (2018)

Estrogen relaxes gastric muscle cells via a nitric oxide- and cyclic guanosine monophosphate-dependent mechanism: A sex-associated differential effect
por: Al-Shboul, Othman A., et al.
Publicado: (2018)

Light-initiated changes of cyclic guanosine monophosphate levels in the frog retina measured with quick-freezing techniques
Publicado: (1979)

A Cyclic Guanosine Monophosphate–Dependent Pathway Can Regulate Net Hepatic Glucose Uptake in Vivo
por: An, Zhibo, et al.
Publicado: (2012)

FRI669 Skeletal Effect Of Cyclic Guanosine Monophosphate Dependent Protein Kinase G Type 2
por: Kim, Se Min, et al.
Publicado: (2023)

The cyclic guanosine monophosphate synthase-stimulator of interferon genes pathway as a potential target for tumor immunotherapy
por: Chen, Rui, et al.
Publicado: (2023)

Temperature and pressure limits of guanosine monophosphate self-assemblies
por: Gao, Mimi, et al.
Publicado: (2017)

Calcium effects on frog retinal cyclic guanosine 3’,5’- monophosphate levels and their light-initiated rate of decay
por: Kilbride, P
Publicado: (1980)

Cyclic Guanosine Monophosphate-Dependent Protein Kinase I Stimulators and Activators Are Therapeutic Alternatives for Sickle Cell Disease
por: Ghanta, Mohankrishna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5oaf1sk6s8d0rgg4ooc0hig3h0