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Fast and accurate approximate inference of transcript expression from RNA-seq data

Motivation: Assigning RNA-seq reads to their transcript of origin is a fundamental task in transcript expression estimation. Where ambiguities in assignments exist due to transcripts sharing sequence, e.g. alternative isoforms or alleles, the problem can be solved through probabilistic inference. Ba...

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Detalles Bibliográficos
Autores principales: Hensman, James, Papastamoulis, Panagiotis, Glaus, Peter, Honkela, Antti, Rattray, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673974/
https://www.ncbi.nlm.nih.gov/pubmed/26315907
http://dx.doi.org/10.1093/bioinformatics/btv483