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SOD2 genetic variant associated with treatment-related ototoxicity in cisplatin-treated pediatric medulloblastoma
Manganese superoxide dismutase (MnSOD), encoded by the SOD2 gene, is involved in the detoxification of superoxide anion. Superoxide is likely a source of oxidative stress in the cochlea following treatment with platinum agents and radiation. Therefore, we examined SOD2 variants in association with o...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673994/ https://www.ncbi.nlm.nih.gov/pubmed/26400460 http://dx.doi.org/10.1002/cam4.516 |