Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients

Large size, protein binding and intracellular sequestration are well known to limit dialytic removal of compounds. In studying the normal renal and dialytic handling of trimethylamine oxide (TMAO), a molecule associated with cardiovascular disease in the general population, we discovered two largely...

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Detalles Bibliográficos
Autores principales: Hai, Xin, Landeras, Veeda, Dobre, Mirela A., DeOreo, Peter, Meyer, Timothy W., Hostetter, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674074/
https://www.ncbi.nlm.nih.gov/pubmed/26650937
http://dx.doi.org/10.1371/journal.pone.0143731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674074/
https://www.ncbi.nlm.nih.gov/pubmed/26650937
http://dx.doi.org/10.1371/journal.pone.0143731

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