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Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos

Although Amiodarone, a class III antiarrhythmic drug, inhibits zebrafish cardiac valve formation, the detailed molecular pathway is still unclear. Here, we proved that Amiodarone acts as an upstream regulator, stimulating similar to versican b (s-vcanb) overexpression at zebrafish embryonic heart an...

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Detalles Bibliográficos
Autores principales:	Lee, Hung-Chieh, Lo, Hao-Chan, Lo, Dao-Ming, Su, Mai-Yan, Hu, Jia-Rung, Wu, Chin-Chieh, Chang, Sheng-Nan, Dai, Ming-Shen, Tsai, Chia‐Ti, Tsai, Huai-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674151/ https://www.ncbi.nlm.nih.gov/pubmed/26650936 http://dx.doi.org/10.1371/journal.pone.0144751

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