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Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

Controlled human malaria infection (CHMI) is a powerful tool to evaluate malaria vaccine and prophylactic drug efficacy. Until recently CHMI was only carried out by the bite of infected mosquitoes. A parenteral method of CHMI would standardize Plasmodium falciparum sporozoite (PfSPZ) administration,...

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Detalles Bibliográficos
Autores principales:	Lyke, Kirsten E., Laurens, Matthew B., Strauss, Kathy, Adams, Matthew, Billingsley, Peter F., James, Eric, Manoj, Anita, Chakravarty, Sumana, Plowe, Christopher V., Li, Ming Lin, Ruben, Adam, Edelman, Robert, Green, Michael, Dube, Tina J., Kim Lee Sim, B., Hoffman, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Tropical Medicine and Hygiene 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674246/ https://www.ncbi.nlm.nih.gov/pubmed/26416102 http://dx.doi.org/10.4269/ajtmh.15-0341

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