The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

The TAM receptors Tyro3, Axl, and Mertk are receptor tyrosine kinases that dampen host innate immune responses following engagement with their ligands, Gas6 and Protein S, which recognize phosphatidylserine on apoptotic cells. In a form of apoptotic mimicry, many enveloped viruses display phosphatid...

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Detalles Bibliográficos
Autores principales: Miner, Jonathan J., Daniels, Brian P., Shrestha, Bimmi, Proenca-Modena, Jose L., Lew, Erin D., Lazear, Helen M., Gorman, Matthew J., Lemke, Greg, Klein, Robyn S., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674389/
https://www.ncbi.nlm.nih.gov/pubmed/26523970
http://dx.doi.org/10.1038/nm.3974

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