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Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia

BACKGROUND: Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. OBJECTIVE: The objective of this study was to de...

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Autores principales: Jatau, Abubakar Ibrahim, Aung, Myat Moe Thwe, Kamauzaman, Tuan Hairulnizam Tuan, Rahman, Ab Fatah Ab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674517/
https://www.ncbi.nlm.nih.gov/pubmed/26689834
http://dx.doi.org/10.1007/s40801-015-0045-2
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author Jatau, Abubakar Ibrahim
Aung, Myat Moe Thwe
Kamauzaman, Tuan Hairulnizam Tuan
Rahman, Ab Fatah Ab
author_facet Jatau, Abubakar Ibrahim
Aung, Myat Moe Thwe
Kamauzaman, Tuan Hairulnizam Tuan
Rahman, Ab Fatah Ab
author_sort Jatau, Abubakar Ibrahim
collection PubMed
description BACKGROUND: Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. OBJECTIVE: The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. METHODOLOGY: A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. RESULTS: Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. CONCLUSION: The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety.
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spelling pubmed-46745172015-12-17 Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia Jatau, Abubakar Ibrahim Aung, Myat Moe Thwe Kamauzaman, Tuan Hairulnizam Tuan Rahman, Ab Fatah Ab Drugs Real World Outcomes Original Research Article BACKGROUND: Data on the prevalence of adverse drug event (ADE)-related emergency department (ED) visits in developing countries are limited. Malaysia is located in South-East Asia, and, to our knowledge, no information exists on ADE-related ED visits. OBJECTIVE: The objective of this study was to determine the prevalence, preventability, severity, and outcome of drug-related ED visits. METHODOLOGY: A cross-sectional study was conducted in consenting patients who visited the ED of Hospital Universiti Sains Malaysia over a 6-week period. The ED physician on duty determined whether or not the visit was drug related according to set criteria. Other relevant information was extracted from the patient’s medical folder by a clinical pharmacist. RESULTS: Of the 434 consenting patients, 133 (30.6 %; 95 % confidence interval [CI] 26–35 %) visits were determined to be ADE related; 55.5 % were considered preventable, 11.3 % possibly preventable, and 33.1 % not preventable. Severity was classed as mild in 1.5 %, moderate in 67.7 %, and severe in 30.8 %. The most common ADEs reported were drug therapeutic failure (55.6 %) and adverse drug reactions (32.3 %). The most frequently implicated drugs were antidiabetics (n = 31; 23.3 %), antihypertensives (n = 28; 21.1 %), antibiotics (n = 13; 9.8 %), and anti-asthmatics (n = 11; 8.3 %). A total of 93 patients (69.9 %) were admitted to the ED for observation, 25 (18.8 %) were discharged immediately after consultation, and 15 (11.3 %) were admitted to the ward through the ED. CONCLUSION: The prevalence of ADE-related ED visits was high; more than one-half of the events were considered preventable and one-third was classed as severe. As such, preventive measures will minimize future occurrences and increase patient safety. Springer International Publishing 2015-10-23 /pmc/articles/PMC4674517/ /pubmed/26689834 http://dx.doi.org/10.1007/s40801-015-0045-2 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Research Article
Jatau, Abubakar Ibrahim
Aung, Myat Moe Thwe
Kamauzaman, Tuan Hairulnizam Tuan
Rahman, Ab Fatah Ab
Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title_full Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title_fullStr Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title_full_unstemmed Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title_short Prevalence of Drug-Related Emergency Department Visits at a Teaching Hospital in Malaysia
title_sort prevalence of drug-related emergency department visits at a teaching hospital in malaysia
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674517/
https://www.ncbi.nlm.nih.gov/pubmed/26689834
http://dx.doi.org/10.1007/s40801-015-0045-2
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