Endoscopic Disease Activity in Inflammatory Bowel Disease

Endoscopic scoring systems in Crohn’s disease and ulcerative colitis aim to translate the assessment of mucosal disease activity into a quantified value. This value seeks to provide a clear, objective record of the endoscopic mucosal severity, which can then be used to guide medical management decis...

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Detalles Bibliográficos
Autores principales: Ket, Shara Nguyen, Palmer, Rebecca, Travis, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Inflammatory Bowel Disease (S Hanauer, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674531/
https://www.ncbi.nlm.nih.gov/pubmed/26650939
http://dx.doi.org/10.1007/s11894-015-0470-0
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author Ket, Shara Nguyen
Palmer, Rebecca
Travis, Simon
author_facet Ket, Shara Nguyen
Palmer, Rebecca
Travis, Simon
author_sort Ket, Shara Nguyen
collection PubMed
description Endoscopic scoring systems in Crohn’s disease and ulcerative colitis aim to translate the assessment of mucosal disease activity into a quantified value. This value seeks to provide a clear, objective record of the endoscopic mucosal severity, which can then be used to guide medical management decisions. The primary driver of all endoscopic indices, however, is to define a scale of responsiveness for therapeutic endpoints in clinical trials. Mucosal healing now has widespread acceptance as a therapeutic and clinical endpoint, but despite the development of multiple endoscopic scoring systems, the endoscopic definition has yet to be resolved. This review describes recent advances in endoscopic scoring systems for ulcerative colitis (Mayo Clinic endoscopy subscore, UCEIS, and UCCIS among others) and for Crohn’s disease.
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spelling pubmed-46745312015-12-17 Endoscopic Disease Activity in Inflammatory Bowel Disease Ket, Shara Nguyen Palmer, Rebecca Travis, Simon Curr Gastroenterol Rep Inflammatory Bowel Disease (S Hanauer, Section Editor) Endoscopic scoring systems in Crohn’s disease and ulcerative colitis aim to translate the assessment of mucosal disease activity into a quantified value. This value seeks to provide a clear, objective record of the endoscopic mucosal severity, which can then be used to guide medical management decisions. The primary driver of all endoscopic indices, however, is to define a scale of responsiveness for therapeutic endpoints in clinical trials. Mucosal healing now has widespread acceptance as a therapeutic and clinical endpoint, but despite the development of multiple endoscopic scoring systems, the endoscopic definition has yet to be resolved. This review describes recent advances in endoscopic scoring systems for ulcerative colitis (Mayo Clinic endoscopy subscore, UCEIS, and UCCIS among others) and for Crohn’s disease. Springer US 2015-12-09 2015 /pmc/articles/PMC4674531/ /pubmed/26650939 http://dx.doi.org/10.1007/s11894-015-0470-0 Text en © The Author(s) 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Inflammatory Bowel Disease (S Hanauer, Section Editor)
Ket, Shara Nguyen
Palmer, Rebecca
Travis, Simon
Endoscopic Disease Activity in Inflammatory Bowel Disease
title Endoscopic Disease Activity in Inflammatory Bowel Disease
title_full Endoscopic Disease Activity in Inflammatory Bowel Disease
title_fullStr Endoscopic Disease Activity in Inflammatory Bowel Disease
title_full_unstemmed Endoscopic Disease Activity in Inflammatory Bowel Disease
title_short Endoscopic Disease Activity in Inflammatory Bowel Disease
title_sort endoscopic disease activity in inflammatory bowel disease
topic Inflammatory Bowel Disease (S Hanauer, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674531/
https://www.ncbi.nlm.nih.gov/pubmed/26650939
http://dx.doi.org/10.1007/s11894-015-0470-0
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