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Genetic Resistance Determinants, In Vitro Time-Kill Curve Analysis and Pharmacodynamic Functions for the Novel Topoisomerase II Inhibitor ETX0914 (AZD0914) in Neisseria gonorrhoeae

Resistance in Neisseria gonorrhoeae to all available therapeutic antimicrobials has emerged and new efficacious drugs for treatment of gonorrhea are essential. The topoisomerase II inhibitor ETX0914 (also known as AZD0914) is a new spiropyrimidinetrione antimicrobial that has different mechanisms of...

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Detalles Bibliográficos
Autores principales:	Foerster, Sunniva, Golparian, Daniel, Jacobsson, Susanne, Hathaway, Lucy J., Low, Nicola, Shafer, William M., Althaus, Christian L., Unemo, Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674575/ https://www.ncbi.nlm.nih.gov/pubmed/26696986 http://dx.doi.org/10.3389/fmicb.2015.01377

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