Treatment with PPARα Agonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens

PPARα agonist clofibrate reduces cholesterol and fatty acid concentrations in rodent liver by an inhibition of SREBP-dependent gene expression. In present study we investigated the regulation mechanisms of the triglyceride- and cholesterol-lowering effect of the PPARα agonist clofibrate in broiler c...

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Detalles Bibliográficos
Autores principales: Zhang, Lijun, Li, Chunyan, Wang, Fang, Zhou, Shenghua, Shangguan, Mingjun, Xue, Lina, Zhang, Bianying, Ding, Fuxiang, Hui, Dequan, Liang, Aihua, He, Dongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674622/
https://www.ncbi.nlm.nih.gov/pubmed/26693219
http://dx.doi.org/10.1155/2015/347245

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