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Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels
Injury to podocytes is considered a major contributor to diabetic kidney disease: their loss causes proteinuria and progressive glomerulosclerosis. Podocyte depletion may result from improper calcium handling due to abnormal activation of the calcium permeant TRPC (Transient Receptor Potential Canon...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674698/ https://www.ncbi.nlm.nih.gov/pubmed/26656101 http://dx.doi.org/10.1038/srep17637 |