Cargando…

Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels

Injury to podocytes is considered a major contributor to diabetic kidney disease: their loss causes proteinuria and progressive glomerulosclerosis. Podocyte depletion may result from improper calcium handling due to abnormal activation of the calcium permeant TRPC (Transient Receptor Potential Canon...

Descripción completa

Detalles Bibliográficos
Autores principales: Ilatovskaya, Daria V., Levchenko, Vladislav, Lowing, Andrea, Shuyskiy, Leonid S., Palygin, Oleg, Staruschenko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674698/
https://www.ncbi.nlm.nih.gov/pubmed/26656101
http://dx.doi.org/10.1038/srep17637