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Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels

Injury to podocytes is considered a major contributor to diabetic kidney disease: their loss causes proteinuria and progressive glomerulosclerosis. Podocyte depletion may result from improper calcium handling due to abnormal activation of the calcium permeant TRPC (Transient Receptor Potential Canon...

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Detalles Bibliográficos
Autores principales: Ilatovskaya, Daria V., Levchenko, Vladislav, Lowing, Andrea, Shuyskiy, Leonid S., Palygin, Oleg, Staruschenko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674698/
https://www.ncbi.nlm.nih.gov/pubmed/26656101
http://dx.doi.org/10.1038/srep17637

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