Reactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives

Both amyloid-β (Aβ) and transition metal ions are shown to be involved in the pathogenesis of Alzheimer’s disease (AD), though the importance of their interactions remains unclear. Multifunctional molecules, which can target metal-free and metal-bound Aβ and modulate their reactivity (e.g., Aβ aggre...

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Detalles Bibliográficos
Autores principales: Korshavn, Kyle J., Jang, Milim, Kwak, Yeon Ju, Kochi, Akiko, Vertuani, Silvia, Bhunia, Anirban, Manfredini, Stefano, Ramamoorthy, Ayyalusamy, Lim, Mi Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674742/
https://www.ncbi.nlm.nih.gov/pubmed/26657338
http://dx.doi.org/10.1038/srep17842

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