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Selective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) Ligand

[Image: see text] As the delivery of selectively targeted cytotoxic agents via antibodies or small molecule ligands to malignancies has begun to show promise in the clinic, the need to identify and validate additional cellular targets for specific therapeutic delivery is critical. Although a multitu...

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Detalles Bibliográficos
Autores principales: Wayua, Charity, Roy, Jyoti, Putt, Karson S., Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674820/
https://www.ncbi.nlm.nih.gov/pubmed/26043355
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00218