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A computational method for drug repositioning using publicly available gene expression data

MOTIVATION: The identification of new therapeutic uses of existing drugs, or drug repositioning, offers the possibility of faster drug development, reduced risk, lesser cost and shorter paths to approval. The advent of high throughput microarray technology has enabled comprehensive monitoring of tra...

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Detalles Bibliográficos
Autores principales: Shabana, KM, Abdul Nazeer, KA, Pradhan, Meeta, Palakal, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674855/
https://www.ncbi.nlm.nih.gov/pubmed/26679199
http://dx.doi.org/10.1186/1471-2105-16-S17-S5

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