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Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway
The present work aimed to investigate the activities and underlying mechanisms of dioscin against alcoholic liver fibrosis (ALF). In vivo liver fibrosis in mice was induced by an alcoholic liquid diet, and in vitro studies were performed on activated HSC-T6 and LX2 cells treated with lipopolysacchar...
Autores principales: | Liu, Min, Xu, Youwei, Han, Xu, Yin, Lianhong, Xu, Lina, Qi, Yan, Zhao, Yanyan, Liu, Kexin, Peng, Jinyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674875/ https://www.ncbi.nlm.nih.gov/pubmed/26655640 http://dx.doi.org/10.1038/srep18038 |
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