How genome complexity can explain the difficulty of aligning reads to genomes

BACKGROUND: Although it is frequently observed that aligning short reads to genomes becomes harder if they contain complex repeat patterns, there has not been much effort to quantify the relationship between complexity of genomes and difficulty of short-read alignment. Existing measures of sequence...

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Detalles Bibliográficos
Autores principales: Phan, Vinhthuy, Gao, Shanshan, Tran, Quang, Vo, Nam S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674900/
https://www.ncbi.nlm.nih.gov/pubmed/26678826
http://dx.doi.org/10.1186/1471-2105-16-S17-S3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674900/
https://www.ncbi.nlm.nih.gov/pubmed/26678826
http://dx.doi.org/10.1186/1471-2105-16-S17-S3

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