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How genome complexity can explain the difficulty of aligning reads to genomes
BACKGROUND: Although it is frequently observed that aligning short reads to genomes becomes harder if they contain complex repeat patterns, there has not been much effort to quantify the relationship between complexity of genomes and difficulty of short-read alignment. Existing measures of sequence...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674900/ https://www.ncbi.nlm.nih.gov/pubmed/26678826 http://dx.doi.org/10.1186/1471-2105-16-S17-S3 |