High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants

BACKGROUND: Mycobacterium abscessus (MAB) is an emerging pathogen causing pulmonary infections in those with inflammatory lung disorders, such as Cystic Fibrosis (CF), and is associated with the highest fatality rate among rapidly growing mycobacteria (RGM). Phenotypically, MAB manifests as either a...

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Detalles Bibliográficos
Autores principales: Aulicino, Anna, Dinan, Adam M., Miranda-CasoLuengo, Aleksandra A., Browne, John A., Rue-Albrecht, Kévin, MacHugh, David E., Loftus, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674915/
https://www.ncbi.nlm.nih.gov/pubmed/26654095
http://dx.doi.org/10.1186/s12864-015-2246-1

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