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Paracetamol as a toxic substance for children: aspects of legislation in selected countries
Paracetamol is used widely in pediatrics because it has a high drug safety when used in therapeutic dosages. In case of overdose the majority of paracetamol is metabolized to N-acetyl-p-benzoquinone imine (NAPQI), which is responsible for the severe toxic effects. The covalent connection between NAP...
Autores principales: | Mund, Menen E., Quarcoo, David, Gyo, Christoph, Brüggmann, Dörthe, Groneberg, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674926/ https://www.ncbi.nlm.nih.gov/pubmed/26664414 http://dx.doi.org/10.1186/s12995-015-0084-3 |
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