Genetic modification of human mesenchymal stem cells helps to reduce adiposity and improve glucose tolerance in an obese diabetic mouse model

INTRODUCTION: Human mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into fat, muscle, bone and cartilage cells. Exposure of subcutaneous abdominal adipose tissue derived AD-MSCs to high glucose (HG) leads to superoxide accumulation and up-regulation of inflammatory molecul...

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Detalles Bibliográficos
Autores principales: Sen, Sabyasachi, Domingues, Cleyton C., Rouphael, Carol, Chou, Cyril, Kim, Chul, Yadava, Nagendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674936/
https://www.ncbi.nlm.nih.gov/pubmed/26652025
http://dx.doi.org/10.1186/s13287-015-0224-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674936/
https://www.ncbi.nlm.nih.gov/pubmed/26652025
http://dx.doi.org/10.1186/s13287-015-0224-9

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