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A Case Report of Rash at Peritoneal Dialysis Exit Site
The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI). Among these prophylactic antimicrobial preparations, topical gentamicin is one o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674992/ https://www.ncbi.nlm.nih.gov/pubmed/26668811 http://dx.doi.org/10.1177/2324709615618222 |
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author | Gosmanova, Elvira O. Ezumba, Ikena Fisher, Kristopher R. Cleveland, Kerry O. |
author_facet | Gosmanova, Elvira O. Ezumba, Ikena Fisher, Kristopher R. Cleveland, Kerry O. |
author_sort | Gosmanova, Elvira O. |
collection | PubMed |
description | The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI). Among these prophylactic antimicrobial preparations, topical gentamicin is one of the widely used and effective antibiotics for prevention of ESI and peritonitis in peritoneal dialysis (PD) patients. Overall, topical gentamicin is well tolerated; however, its use can be associated with the development of allergic contact dermatitis (ACD). We describe a first reported case of PD catheter exit site contact ACD due to topical gentamicin mimicking ESI. The patient in this report developed worsening violaceous in color and pruritic rash surrounding the PD catheter exit site that appeared 3 weeks after the initiation of gentamicin cream. The association between development of rash and initiation of topical gentamicin led to a suspicion of local reaction to gentamicin rather than ESI. Skin biopsy confirmed ACD. Discontinuation of the provoking agent and subsequent treatment with topical hydrocortisone application led to a resolution of the exit site rash. Any rash at a PD catheter exit site should be considered infectious until proven otherwise. However, it is important to be aware of noninfectious etiologies of exit site rashes as the treatment of these 2 conditions differs. |
format | Online Article Text |
id | pubmed-4674992 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-46749922015-12-14 A Case Report of Rash at Peritoneal Dialysis Exit Site Gosmanova, Elvira O. Ezumba, Ikena Fisher, Kristopher R. Cleveland, Kerry O. J Investig Med High Impact Case Rep Article The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI). Among these prophylactic antimicrobial preparations, topical gentamicin is one of the widely used and effective antibiotics for prevention of ESI and peritonitis in peritoneal dialysis (PD) patients. Overall, topical gentamicin is well tolerated; however, its use can be associated with the development of allergic contact dermatitis (ACD). We describe a first reported case of PD catheter exit site contact ACD due to topical gentamicin mimicking ESI. The patient in this report developed worsening violaceous in color and pruritic rash surrounding the PD catheter exit site that appeared 3 weeks after the initiation of gentamicin cream. The association between development of rash and initiation of topical gentamicin led to a suspicion of local reaction to gentamicin rather than ESI. Skin biopsy confirmed ACD. Discontinuation of the provoking agent and subsequent treatment with topical hydrocortisone application led to a resolution of the exit site rash. Any rash at a PD catheter exit site should be considered infectious until proven otherwise. However, it is important to be aware of noninfectious etiologies of exit site rashes as the treatment of these 2 conditions differs. SAGE Publications 2015-11-27 /pmc/articles/PMC4674992/ /pubmed/26668811 http://dx.doi.org/10.1177/2324709615618222 Text en © 2015 American Federation for Medical Research http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Article Gosmanova, Elvira O. Ezumba, Ikena Fisher, Kristopher R. Cleveland, Kerry O. A Case Report of Rash at Peritoneal Dialysis Exit Site |
title | A Case Report of Rash at Peritoneal Dialysis Exit Site |
title_full | A Case Report of Rash at Peritoneal Dialysis Exit Site |
title_fullStr | A Case Report of Rash at Peritoneal Dialysis Exit Site |
title_full_unstemmed | A Case Report of Rash at Peritoneal Dialysis Exit Site |
title_short | A Case Report of Rash at Peritoneal Dialysis Exit Site |
title_sort | case report of rash at peritoneal dialysis exit site |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674992/ https://www.ncbi.nlm.nih.gov/pubmed/26668811 http://dx.doi.org/10.1177/2324709615618222 |
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