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Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms

PURPOSE: To describe a new technique to record focal macular electroretinograms (FMERGs) during vitrectomy to assess macular function. METHODS: Intraoperative FMERGs (iFMERGs) were recorded in ten patients (10 eyes) who undergo vitrectomy. iFMERGs were elicited by focal macular stimulation. The stim...

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Autores principales: Matsumoto, Celso Soiti, Shinoda, Kei, Terauchi, Gaku, Matsumoto, Harue, Mizota, Atsushi, Miyake, Yozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675556/
https://www.ncbi.nlm.nih.gov/pubmed/26658489
http://dx.doi.org/10.1371/journal.pone.0144627
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author Matsumoto, Celso Soiti
Shinoda, Kei
Terauchi, Gaku
Matsumoto, Harue
Mizota, Atsushi
Miyake, Yozo
author_facet Matsumoto, Celso Soiti
Shinoda, Kei
Terauchi, Gaku
Matsumoto, Harue
Mizota, Atsushi
Miyake, Yozo
author_sort Matsumoto, Celso Soiti
collection PubMed
description PURPOSE: To describe a new technique to record focal macular electroretinograms (FMERGs) during vitrectomy to assess macular function. METHODS: Intraoperative FMERGs (iFMERGs) were recorded in ten patients (10 eyes) who undergo vitrectomy. iFMERGs were elicited by focal macular stimulation. The stimulus light was directed to the macular area through a 25 gauge (25G) glass fiber optic bundle. Background light was delivered through a dual chandelier-type light fiber probe. Focal macular responses elicited with combinations of stimulus and background luminances were analyzed. RESULTS: A stimulus luminance that was approximately 1.75 log units brighter than the background light was able to elicit focal macular responses that were not contaminated by stray light responses. Thus, a stimulus luminance of 160 cd/m(2) delivered on a background of 3 cd/m(2) elicited iFMEGs from only the stimulated area. This combination of stimulus and background luminances did not elicit a response when the stimulus was projected onto the optic nerve head. The iFMERGs elicited by a 10° stimulus with a duration of 100 ms and an interstimulus interval of 150 ms consisted of an a-, b-, and d-waves, the oscillatory potentials, and the photopic negative response (PhNR). CONCLUSIONS: Focal ERGs with all components can be recorded from the macula and other retinal areas during vitreous surgery. This new technique will allow surgeons to assess the function of focal areas of the retina intraoperatively.
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spelling pubmed-46755562015-12-31 Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms Matsumoto, Celso Soiti Shinoda, Kei Terauchi, Gaku Matsumoto, Harue Mizota, Atsushi Miyake, Yozo PLoS One Research Article PURPOSE: To describe a new technique to record focal macular electroretinograms (FMERGs) during vitrectomy to assess macular function. METHODS: Intraoperative FMERGs (iFMERGs) were recorded in ten patients (10 eyes) who undergo vitrectomy. iFMERGs were elicited by focal macular stimulation. The stimulus light was directed to the macular area through a 25 gauge (25G) glass fiber optic bundle. Background light was delivered through a dual chandelier-type light fiber probe. Focal macular responses elicited with combinations of stimulus and background luminances were analyzed. RESULTS: A stimulus luminance that was approximately 1.75 log units brighter than the background light was able to elicit focal macular responses that were not contaminated by stray light responses. Thus, a stimulus luminance of 160 cd/m(2) delivered on a background of 3 cd/m(2) elicited iFMEGs from only the stimulated area. This combination of stimulus and background luminances did not elicit a response when the stimulus was projected onto the optic nerve head. The iFMERGs elicited by a 10° stimulus with a duration of 100 ms and an interstimulus interval of 150 ms consisted of an a-, b-, and d-waves, the oscillatory potentials, and the photopic negative response (PhNR). CONCLUSIONS: Focal ERGs with all components can be recorded from the macula and other retinal areas during vitreous surgery. This new technique will allow surgeons to assess the function of focal areas of the retina intraoperatively. Public Library of Science 2015-12-10 /pmc/articles/PMC4675556/ /pubmed/26658489 http://dx.doi.org/10.1371/journal.pone.0144627 Text en © 2015 Matsumoto et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Matsumoto, Celso Soiti
Shinoda, Kei
Terauchi, Gaku
Matsumoto, Harue
Mizota, Atsushi
Miyake, Yozo
Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title_full Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title_fullStr Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title_full_unstemmed Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title_short Assessment of Macular Function during Vitrectomy: New Approach Using Intraoperative Focal Macular Electroretinograms
title_sort assessment of macular function during vitrectomy: new approach using intraoperative focal macular electroretinograms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675556/
https://www.ncbi.nlm.nih.gov/pubmed/26658489
http://dx.doi.org/10.1371/journal.pone.0144627
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