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Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer
Immortalization is an important step toward the malignant transformation of human cells and is critically dependent upon telomere maintenance. There are two known mechanisms to maintain human telomeres. The process of telomere maintenance is either mediated through activation of the enzyme telomeras...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675635/ https://www.ncbi.nlm.nih.gov/pubmed/26675332 http://dx.doi.org/10.2147/PGPM.S52808 |