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Safeguarding CRISPR-Cas9 gene drives in yeast

RNA-guided gene drives capable of spreading genomic alterations made in laboratory organisms through wild populations in an inheritable way could be used to control populations of organisms that cause environmental and public health problems. However, the possibility of unintended genome editing thr...

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Detalles Bibliográficos
Autores principales: DiCarlo, James E., Chavez, Alejandro, Dietz, Sven L., Esvelt, Kevin M., Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675690/
https://www.ncbi.nlm.nih.gov/pubmed/26571100
http://dx.doi.org/10.1038/nbt.3412